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Adaptin γ Mouse, Unlabeled, Clone: 88, BD
Mouse Monoclonal Antibody
186.18 € - 323.14 €
Spezifikation
| Antigen | Adaptin γ |
|---|---|
| Klon | 88 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15845429
|
BD Biosciences
610385 |
50 μg |
 187.00 € 186.18 € / 1 Set Sparen 0.82 € 0.44% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15855429
|
BD Biosciences
610386 |
150 μg |
325.00 € 323.14 € / 1 Set Sparen 1.86 € 0.57% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins (γ, α, δ, or ε and β1, β2, β3, β4 respectively) that are noncovalently linked to one medium chain (μ1, μ2, μ3, or μ4) and one small chain ( σ1, σ2, σ3, or σ4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. Adaptin ? shows more homology with Adaptin α than with Adaptin β. The conserved regions between Adaptins γ and α could be important for binding to other components of the AP-1 and AP-2 complexes, respectively.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Spezifikation
| Adaptin γ | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 88 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human, Mouse, Rat | |
| Mouse Adaptin γ aa. 642-821 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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