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CD123 Mouse anti-Human, PE-Cy5, Clone: 9F5, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 551065
Artikelnummer. 15896498
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339.00 €
338.12 € / 1 Stück
Sparen 0.88 €
0.26% Rabatt
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Beschreibung
The 9F5 monoclonal antibody specifically binds to CD123. CD123 is the 70 kDa IL-3 receptor α; chain (IL-3Rα;) that associates with the 120-140 kDa β; subunit (CD131/Common β;-chain/β;c) to form the functional IL-3 receptor complex. The β;c chain is also shared with distinct α; chain subunits to form the functional heterodimeric receptors for interleukins IL-5 and GM-CSF. IL-3Rα; is expressed on a subset of peripheral blood dendritic cells, myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα; is also expressed on lymphocytes. The IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor.
Spezifikation
| CD123 | |
| Monoclonal | |
| PE-Cyanine5 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human IL-3Rα Transfected Cell Line | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 9F5 | |
| IL-3 Receptor α chain | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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