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CD197 (CCR7) Mouse anti-Human, V450, Clone: 150503, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 560864
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Beschreibung
The monoclonal antibody 150503 specifically binds to the human CC chemokine receptor, CCR7, also known as CD197. CCR7 (previously known as BLR2, EBI1 and CMKBR7), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokines, MIP-3β/Exodus 3/ELC/ CCL19 and 6Ckine/Exodus 2/SLC/TCA4/CCL21. CCR7 mRNA is expressed mainly in lymphoid tissues including spleen, lymph nodes and tonsil. CCR7 is expressed on peripheral T and B lymphocytes, by bone marrow and cord blood CD34-positive cells and by mature dendritic cells. Differential CCR7 expression can be used to distinguish naive, central memory and effector memory T cell subsets. The human CCR7 gene, unlike other CC chemokine receptor genes, has been mapped to chromosome 17 (region 17q12).
Spezifikation
| CD197 | |
| Monoclonal | |
| Violet Fluor 450 (V450) | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Human CCR7 Transfected Cell Line | |
| 30 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 150503 | |
| CC chemokine receptor 7; BLR2; CMKBR7; EBI1; EVI1; MIP-3 beta receptor | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2a |
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