anti-Eosinophil Major Basic Protein, Clone: BMK-13 MA135360, Invitrogen™

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.

Host Species: Mouse

Cross Reactivity: Human

Isotype: IgG1

Clone: BMK-13

Immunogen: MBP.

Formulation: 1mL of purified antibody (0.1mg/mL) in PBS buffer, with BSA 0.1%;

Uniprot Accession: P13727

Gene Symbol: PRG2

MA1-35360 detects Eosinophil Major Basic Protein in Human samples. MA1-35360 has been successfully used in ELISA and IHC procedures.MA1-35360 The immunogen is MBP.