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IFN-α (2b) Mouse anti-Human, NA/LE, Unlabeled, Clone: 7N4-1, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 551795
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Beschreibung
The 7N4-1 antibody reacts with human IFN-α2b and to a lesser extent with IFN-α7. It does not react with IFN-α1 nor IFN-α4. IFN-α2b is one of the three variants of IFN-α2 that have been isolated from human cell lines. IFN-α2b is the variant predominantly produced by human leukocytes. Human IFN-α2b belongs to the IFN-α class of proteins also known as leukocyte interferons. IFN-α comprises a family of related but distinct proteins with molecular weights ranging from 16-27kDa with antiviral, antiproliferative and immunomodulatory activities. The IFN-α family is composed from as many as 14 different genes. The immunogen used to generate the 7N4-1 hybridoma was E. coli-expressed recombinant human IFN-α2b. This is a neutralizing antibody.
Host Species: Mouse
Clone: 7N4-1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: E. coli-expressed recombinant human IFN-α2b
Functional Assay, Immunohistochemistry
Spezifikation
| IFN-α (2b) | |
| Monoclonal | |
| 1.0mg/mL | |
| IFNa, IFNα | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 7N4-1 | |
| Unconjugated | |
| No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. | |
| E. coli-expressed recombinant human IFN-α2b | |
| 0.5 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
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