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IFN-α (2b) Mouse anti-Human, NA/LE, Unlabeled, Clone: 7N4-1, BD
Beschreibung
The 7N4-1 antibody reacts with human IFN-α2b and to a lesser extent with IFN-α7. It does not react with IFN-α1 nor IFN-α4. IFN-α2b is one of the three variants of IFN-α2 that have been isolated from human cell lines. IFN-α2b is the variant predominantly produced by human leukocytes. Human IFN-α2b belongs to the IFN-α class of proteins also known as leukocyte interferons. IFN-α comprises a family of related but distinct proteins with molecular weights ranging from 16-27kDa with antiviral, antiproliferative and immunomodulatory activities. The IFN-α family is composed from as many as 14 different genes. The immunogen used to generate the 7N4-1 hybridoma was E. coli-expressed recombinant human IFN-α2b. This is a neutralizing antibody.
Host Species: Mouse
Clone: 7N4-1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: E. coli-expressed recombinant human IFN-α2b
Functional Assay, Immunohistochemistry
Spezifikation
Spezifikation
| Antigen | IFN-α (2b) |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Klon | 7N4-1 |
| Konzentration | 1.0mg/mL |
| Konjugat | Unconjugated |
| Beschreibung | IFNa, IFNα |
| Zusammensetzung | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. |
| Wirtsspezies | Mouse |
| Immunogen | E. coli-expressed recombinant human IFN-α2b |
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For Research Use Only.
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