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PKA (RIIα) Mouse, Unlabeled, Clone: 40, BD
Mouse Monoclonal Antibody
236.47 € - 323.14 €
Spezifikation
| Antigen | PKA (RIIα) |
|---|---|
| Klon | 40 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15836139
|
BD Biosciences
612242 |
50 μg |
 251.00 € 236.47 € / 1 Set Sparen 14.53 € 5% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15846139
|
BD Biosciences
612243 |
150 μg |
325.00 € 323.14 € / 1 Set Sparen 1.86 € 0.57% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic(C) and regulatory (R). Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ.These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. Most cells express both type I and type II PKAs. Although the Rα isoforms are ubiquitously expressed, the Rβ isoforms are predominant in nervous and adipose tissues. Expression of the RIα subunit is modulated during muscle and adipocyte differentiation in vitro.
Immunofluorescence, Immunoprecipitation, Western Blotting
Spezifikation
| PKA (RIIα) | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 40 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human, Mouse, Rat | |
| Human PKA[RIIα] aa. 1-404 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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