missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Prostasin Mouse anti-Human, Unlabeled, Clone: 2, BD
Mouse Monoclonal Antibody
329.00 € - 379.85 €
Spezifikation
| Antigen | Prostasin |
|---|---|
| Klon | 2 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15826129
|
BD Biosciences
612172 |
50 μg | |||||||
|
15836129
|
BD Biosciences
612173 |
150 μg |
 380.00 € 379.85 € / 1 Set Sparen 0.15 € 0.04% Rabatt |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | |||||
Beschreibung
Prostasin is a serine protease expressed as both GPI-anchored and secreted forms. Prostasin displays trypsin-like enzymatic activity by hydrolyzing substrates, such as D-Pro-Phe-Arg-AMC. This activity is inhibited by aprotinin, antipain, leupeptin, and benzamidine. The highest levels of prostasin protein are found in semen and the prostate, but many other tissues express prostasin at low levels. The sequence of prostasin is similar to other proteases, such as prostase, testisin, plasma kallikrein, and acrosin. In seminal fluid, prostasin can be found in complex with prostasin-binding protein, which can inhibit prostasin enzymatic activity. Prostasin mRNA is found in normal prostate epithelial cells and non-invasive prostate cancer cells, but is not expressed in invasive prostate cancer cell lines. Expression of prostasin in the invasive prostate cancer cell lines, DU-145 and PC-3, reduces the invasiveness of the cells in vitro. Thus, prostasin is a serine protease that may have roles in normal prostate function and in suppression of tumor cell invasion.
Western Blotting
Spezifikation
| Prostasin | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2a | |
| Affinity Purified |
| 2 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human | |
| Human Prostasin aa. 108-228 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
Haben Sie Verbesserungsvorschläge?Übermitteln Sie eine inhaltliche Korrektur
Berichtigung von Produktinhalten
Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.
Name des Produkts