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RORγt Mouse anti-Mouse, PE, Clone: Q31-378, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 562607
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Beschreibung
The Q31-378 monoclonal antibody recognizes RORgamma t (RORγt), an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. RORγt is expressed exclusively by lymphoid cells including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells, NKT cells and innate lymphoid cells such as lymphoid tissue inducer (LTi) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer's patches.
Host Species: Mouse
Clone: Q31-378
Isotype: IgG2a, κ
Species Reactivity: Mouse
Immunogen: Mouse RORγt Recombinant Protein
Intracellular Staining
Spezifikation
| RORγt | |
| Monoclonal | |
| 0.2mg/mL | |
| RORγT; RORgt; RORgamma t; RORgammaT; Rorc2; Rorg; TOR; Thor; Nr1f3 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2a κ |
| Flow Cytometry | |
| Q31-378 | |
| PE | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse RORγt Recombinant Protein | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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