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Invitrogen™ Aquaporin 2 Recombinant Rabbit Monoclonal Antibody (24GB6835)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA556968
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Beschreibung
Aquaporin 2 Recombinant Monoclonal Antibody for Western Blot
Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.
Spezifikation
| Aquaporin 2 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Aqp2 | |
| ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 359 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB6835 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P41181 | |
| Aqp2 | |
| A synthesized peptide derived from human Aquaporin 2 (aa 191-202). | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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