missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ARHGEF7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Spezifikation
| Antigen | ARHGEF7 |
|---|---|
| Konzentration | 0.27 mg/mL |
| Anwendungen | Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence |
| Klassifikation | Polyclonal |
| Konjugat | Unconjugated |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
16812584
|
Proteintech
14092-1-AP-20UL |
20 μL |
145.00 €
20 Mikroliter |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
16802584
|
Proteintech
14092-1-AP-150UL |
150 μL |
410.00 €
150 Mikroliter |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
The serine/threonine kinase, p21 activated kinase (PAK), is a downstream effector of the small GTPases Cdc42 and Rac. PAK associates with Nck, the p85 and p110 subunits of PI3-kinase and PIX (PAK-interacting exchange factor) in a focal complex. The binding of PIX is necessary for the localization and activation of PAK in the Cdc42 to Rac signaling pathway, and this binding occurs through the high affinity of the N-terminal SH3 domain of PIX for a conserved proline rich PAK sequence. PIX exists as two isoforms, alpha and beta, and both are highly expressed in heart, muscle and thymus tissues of human and rat. alphaPIX is phosphorylated via PDGF and EphB2 receptor signaling pathways or through association with PI3-kinase. The alphaPIX isoform predomitly acts as a guanine nucleotide exchange factor (GEF) on Rac, which may mediate lamellipodia formation.Spezifikation
| ARHGEF7 | |
| Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence | |
| Unconjugated | |
| Rabbit | |
| Human, Rat, Mouse | |
| O55043, Q14155, Q9ES28 | |
| 114559, 54126, 8874 | |
| ARHGEF7 Fusion Protein Ag5223 | |
| Primary | |
| -20°C | |
| ARHGEF7 |
| 0.27 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| ARHGEF7, BETA PIX, COOL 1, COOL1, KIAA0142, KIAA0412, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PAK3BP, PIXB | |
| Arhgef7 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
Haben Sie Verbesserungsvorschläge?Übermitteln Sie eine inhaltliche Korrektur
Berichtigung von Produktinhalten
Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.
Name des Produkts