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Beta-Estradiol, 99 % (Trockengewicht), ca. 3 % Wasser, Thermo Scientific Chemicals
Description
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
β-Estradiol ist das wichtigste Östrogen, das vor der Menopause in den Eierstöcken gebildet wird. Agiert als Estrogenrezeptor (ER)-Agonist und aktiviert die PI3-Kinase. Wird zur Behandlung weiblicher Unfruchtbarkeit, bei Prostatakrebs und in der Brustkrebstherapie eingesetzt. Dient auch zur künstlichen Einleitung der Pubertät bei Patientinnen mit Hypogonadismus oder Turner-Syndrom. Kann im Rahmen einer Hormonersatztherapie bei Transgender-Frauen verwendet werden.
Löslichkeit
Löslich in Dimethylsulfoxid, Ethanol, Wasser, phosphatgepufferter Salzlösung, Dimethylformamid, Aceton, Dioxan und Alkalihydroxiden. Geringe Löslichkeit in Pflanzenölen.
Hinweise
Nicht kompatibel mit starken Oxidationsmitteln.
Specifications
Specifications
| Chemischer Name oder Material | beta-Estradiol |
| Schmelzpunkt | 175°C to 178°C |
| Hinweise zum Prozentgehalt | (Trockengewicht), ≈ 3 % Wasser |
| Menge | 5 g |
| Beilstein | 1914275 |
| Merck Index | 14,3703 |
| Löslichkeitsinformationen | Soluble in dimethyl sulfoxide,ethanol ,water,phosphate buffer saline,dimethyl formamide,acetone,dioxane and alkali hydroxides. Slightly soluble in vegetable oils. |
| Optische Drehung | +79° (c=1 in Dioxane) |
| Formelmasse | 272.39 |
| Reinheit (%) | 99% |
RUO – Research Use Only
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