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Brefeldin A, 99 %, Thermo Scientific Chemicals
Beschreibung
Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Die mit Brefeldin A vermittelte Apoptose wurde bei humanen Tumorzellen beobachtet. Es ist ein Antibiotikum, das in der Zellkultur verwendet wird und die Proteinsekretion in Säugetier- und anderen eukaryotischen Zellen hemmt, indem es die Funktion des Golgi-Apparats beeinträchtigt.
Löslichkeit
Löslich in Dimethylsulfoxid, Dichlormethan und Ethanol. Schwer in Wasser löslich.
Hinweise
Kühl lagern. Nicht kompatibel mit starken Oxidationsmitteln.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Brefeldin A |
| Schmelzpunkt | 201°C to 205°C |
| Farbe | Weiß |
| Menge | 50 mg |
| UN-Nummer | UN2811 |
| Beilstein | 25191 |
| Merck Index | 14,1369 |
| Löslichkeitsinformationen | Soluble in dimethylsulfoxide,dichloromethane and ethanol. Slightly soluble in water. |
| IUPAC-Name | (1S,6S,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-on |
| Formelmasse | 280.36 |
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