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Tocris Bioscience™ BSJ-4-116
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Artikelnummer. 18746776
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5 mg
Packungsgröße:
5 Milligramm
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18746776 5 mg 5 Milligramm
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Artikelnummer. 18746776 Lieferant Tocris Bioscience™ Lieferanten-Nr. 7528/5

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Selective CDK12 PROTAC™ Degrader

BSJ-4-116 is a selective CDK12 PROTAC® Degrader. BSJ-4-116 selectively degrades CDK12 over a panel of other kinases and exhibits no degradation of CDK13 or cyclin K. The compound inhibits growth of T-ALL cells and sensitizes them to PARP inhibitor Olaparib (Cat. No. 7579).

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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Specifications

Chemischer Name oder Material N-[7-[(3 R)-3-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-1-piperidinyl]heptyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-4-yl]oxy]acetamide
CAS 2519823-34-6
Menge 5 mg
Ziel Active Degraders
Summenformel C40H49ClN8O8S
Reinheit 0.98
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