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Invitrogen™ Calreticulin Recombinant Rabbit Monoclonal Antibody (7T5B2)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA558021
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Beschreibung
Immunogen sequence: EPAVYFKEQF LDGDGWTSRW IESKHKSDFG KFVLSSGKFY GDEEKDKGLQ TSQDARFYAL SASFEPFSNK GQTLVVQFTV KHEQNIDCGG GYVKLFPNSL DQTDMHGDSE YNIMFGPDIC GPGTKKVHVI FNYKGKNVLI NKDIRCKDDE FTHLYTLIVR PDNTYEVKID NSQVESGSLE DDWDFL.
Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Spezifikation
| Calreticulin | |
| Recombinant Monoclonal | |
| 0.71 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| P14211, P18418, P27797 | |
| CALR | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 18-203 of human Calreticulin (NP_004334.1). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 7T5B2 | |
| Unconjugated | |
| CALR | |
| Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA | |
| Rabbit | |
| Protein A | |
| RUO | |
| 12317, 64202, 811 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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