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Thermo Scientific™ CaptureSelect™ Factor H Affinity Matrix
Alle ansehen Thermo Scientific ProdukteDescription
CaptureSelect Factor H Affinity Matrix is designed for the purification of human complement Factor H from plasma and recombinant sources.
Features of the CaptureSelect Factor H Affinity Matrix include:
- Highly selective for human Factor H with no affinity for other human plasma proteins
- Binds both plasma-derived and recombinant full-length Factor H
- Enables efficient purification of Factor H with high yields and retained activity
- Efficient elution at acidic pH
- Excellent scalability
- Non-animal-derived
The high selectivity and yields obtained using CaptureSelect Factor H Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity in one step.
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created using a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics
Matrix: agarose-based
Average particle size: 65 ± 10 μm
Ligand: CaptureSelect Factor H affinity ligand
Ligand coupling method: epoxide
Binding capacity: > 2 mg Factor H/mL resin
Binding conditions: PBS or TBS, pH 7
Elution conditions: 20 mM citric acid, pH 3
Flow characteristics: 50–200 cm/h (up to 2 bar)
Formulation buffer: 20% (v/v) ethanol
Specifications
Specifications
| Bindungsvermögen | > 2 mg Factor H/mL resin |
| Flussrate | 50 to 200 cm/h (up to 2 bar) |
| Zusammensetzung | 20% (v/v) ethanol |
| Inhalt und Lagerung | Store at 2°C to 8°C. Protect from direct daylight. |
| Partikelgröße | 63 μm |
| Form | Resin Slurry |
| Produktlinie | CaptureSelect |
| Menge | 50 ml |
| Typ | Affinity Resin |
| Ligandentyp | CaptureSelect Factor H Affinity Ligand |
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For Research Use Only. Not for use in diagnostic procedures.
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