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Invitrogen™ Cardiac Troponin T Monoclonal Antibody (13-11)
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Product Code. 11314753
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Menge:
200 μL
Unit Size:
500 Mikroliter
Product Code. Menge unitSize
11314753 200 μL 500 Mikroliter
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Product Code. 11314753

Brand: Invitrogen™ MA512960

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Description

Mouse Monoclonal Antibody

MA5-12960 targets Troponin T Cardiac Isoform in IF/ICC, IHC (P), and IM applications and shows reactivity with Avian, Canine, Chicken, Fish, Guinea Pig, Human, mouse, Porcine, Rabbit, and Rat samples. The MA5-12960 immunogen is purified rabbit cardiac troponin T isoform (TnT4R).

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
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Specifications

Antigen Cardiac Troponin T
Anwendungen Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon 13-11
Konzentration 0.5 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gen TNNT2
Gen-Zugriffsnummer P02642, P09741, P45379, P50752, P50753
Gen-Alias alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T
Gensymbole TNNT2
Wirtsspezies Mouse
Immunogen Purified rabbit cardiac troponin T isoform (TnT4R).
Reinigungsverfahren Affinity chromatography
Menge 200 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 100009428, 100379561, 100622450, 21956, 24837, 396433, 403532, 7139
Zielspezies Avian, Canine, Chicken, Fish, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Inhalt und Lagerung 4°C
Produkttyp Antibody
Form Liquid
Isotype IgG1
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