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CD11b Mouse anti-Human, Unconjugated, Clone: ICRF44, Proteintech
Mouse Monoclonal Antibody
Marke: Proteintech 65116-1-IG-500UG
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Beschreibung
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
Spezifikation
| CD11b | |
| Monoclonal | |
| 0.5 mg/mL | |
| Mouse | |
| Primary | |
| Human, Mouse, Rat | |
| IgG1 |
| Flow Cytometry | |
| ICRF44 | |
| Unconjugated | |
| 100 μg | |
| 3684 | |
| Liquid |
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