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CD134 (OX40) Monoclonal Antibody (ACT35 (ACT-35)), Biotin, eBioscience™, Invitrogen™

Artikelnummer. 17180392
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Menge:
100 Tests
25 Tests
Packungsgröße:
100 Stück
25 Stück
Artikelnummer. Menge unitSize
17180392 100 Tests 100 Stück
17170392 25 Tests 25 Stück
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Artikelnummer. 17180392

Marke: eBioscience 13134742

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Mouse Monoclonal Antibody

Description: The ACT35 monoclonal antibody reacts with human CD134, also known as OX-40. A member of the TNF receptor superfamily, CD134/OX-40 is a 50 kDa type I membrane glycoprotein expressed by activated T lymphocytes. The interaction of CD134 with OX-40L has been implicated in T cell-dependent humoral response, regulation of primary T cell expansion, survival of T cells, size of the memory T cell pool and regulation of tolerance in the CD4^+ T cell compartment. Applications Reported: This ACT35 (ACT-35) antibody has been reported for use in flow cytometric analysis. Applications Tested: This ACT35 (ACT-35) antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen CD134 (OX40)
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Klon ACT35 (ACT-35)
Konzentration 5 μL/Test
Konjugat Biotin
Zusammensetzung PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gen Tnfrsf4
Gen-Zugriffsnummer P43489
Gen-Alias ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; Tnfrsf4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; Txgp1l
Gensymbole Tnfrsf4
Wirtsspezies Mouse
Reinigungsverfahren Affinity chromatography
Menge 100 Tests
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 7293
Zielspezies Human
Inhalt und Lagerung 4° C, do not freeze
Produkttyp Antibody
Form Liquid
Isotype IgG1 κ
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