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Invitrogen™ CD205 Monoclonal Antibody (523218)

Description
Reconstitute at 0.5 mg/mL in sterile PBS.
CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Specifications
Specifications
| Antigen | CD205 |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Klon | 523218 |
| Konzentration | 0.5 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with trehalose and no preservative |
| Gen | LY75 |
| Gen-Zugriffsnummer | O60449 |
| Gen-Alias | CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4 |
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