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Invitrogen™ CD6 Monoclonal Antibody (96123)
Rat Monoclonal Antibody
Marke: Invitrogen™ MA561794
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
Spezifikation
| CD6 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q61003 | |
| CD6 | |
| Mouse myeloma cell line NS0-derived recombinant mouse CD6, Leu18-Gly396. | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Western Blot | |
| 96123 | |
| Unconjugated | |
| CD6 | |
| Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120 | |
| Rat | |
| Protein A/G | |
| RUO | |
| 12511 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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