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Invitrogen™ CD68 Monoclonal Antibody (KP1)

Artikelnummer. 11364823
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Menge:
200 μL
Packungsgröße:
500 Mikroliter
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11364823 200 μL 500 Mikroliter
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Artikelnummer. 11364823 Lieferant Invitrogen™ Lieferanten-Nr. MA513324

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Beschreibung

Mouse Monoclonal Antibody

MA5-13324 targets CD68 in IHC (P) and ICC/IF applications and shows reactivity with Feline, Human, Non-human primate, and Rat samples. Does not react with Canine or Chicken. The MA5-13324 immunogen is subcellular fraction of human alveolar macrophages.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen CD68
Anwendungen Immunohistochemistry (Paraffin), Immunocytochemistry
Klassifikation Monoclonal
Klon KP1
Konzentration 0.5 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.09% sodium azide; pH 7.2
Gen Cd68
Gen-Zugriffsnummer P34810
Gen-Alias CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gensymbole Cd68
Wirtsspezies Mouse
Immunogen Subcellular fraction of human alveolar macrophages.
Reinigungsverfahren Affinity chromatography
Menge 200 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 101099002, 287435, 968
Zielspezies Feline, Human, Monkey, Rat
Inhalt und Lagerung 4°C
Produkttyp Antibody
Form Liquid
Isotype IgG1 κ
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