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Invitrogen™ CD97 Monoclonal Antibody (380905)
Mouse Monoclonal Antibody
Marke: Invitrogen™ MA561169
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
Spezifikation
| CD97 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P48960 | |
| ADGRE5, CD97 | |
| Mouse myeloma cell line NS0-derived recombinant human CD97, Gln21-Gln398. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Neutralization | |
| 380905 | |
| Unconjugated | |
| ADGRE5 | |
| AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 976 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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