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Invitrogen™ Cdc20 Recombinant Rabbit Monoclonal Antibody (3P9Y9)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557922
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Beschreibung
Immunogen sequence: MAQFAFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH SAGRTPGRTP GKSSSKVQTT PSKPGGDRYI PHRSAAQMEV ASFLLSKENQ.
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
Spezifikation
| Cdc20 | |
| Recombinant Monoclonal | |
| 1.53 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| Q12834, Q62623 | |
| CDC20 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC20 (NP_001246.2). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunoprecipitation, Western Blot | |
| 3P9Y9 | |
| Unconjugated | |
| CDC20 | |
| 2310042N09Rik; bA276H19.3; C87100; cdc20; CDC20 cell division cycle 20 homolog; cdc20.S; CDC20A; cell cycle protein p55CDC; cell division cycle 20; cell division cycle 20 homolog; cell division cycle 20 S homeolog; cell division cycle protein 20 homolog; fizzy1; mmCdc20; p55cdc; XELAEV_18025163mg; X-FZY | |
| Rabbit | |
| Protein A | |
| RUO | |
| 64515, 991 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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