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CDC42 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16826353 Shop All Proteintech Products
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16826353 20 μL 20 Mikroliter
16816353 150 μL 150 Mikroliter
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Product Code. 16826353 Supplier Proteintech Supplier No. 101551AP20UL

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Rabbit Polyclonal Antibody

This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis, and cell progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrick syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.

Specifications

Antigen CDC42
Anwendungen Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Klassifikation Polyclonal
Konzentration 0.35 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gen CDC42
Gen-Zugriffsnummer P60766, P60953, Q8CFN2
Gen-Alias CDC42, CDC42Hs, G25K, G25K GTP binding protein
Gensymbole Cdc42
Wirtsspezies Rabbit
Immunogen CDC42 Fusion Protein Ag0207
Reinigungsverfahren Antigen Affinity Chromatography
Menge 20 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 12540, 64465, 998
Zielspezies Mouse, Rat, Human
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Liquid
Isotype IgG
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