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Clotrimazole, Thermo Scientific™
Specific inhibitor of calcium-activated potassium channels
Marke: Thermo Scientific Alfa Aesar J63895.06
| Menge | 5g |
|---|
Artikelnummer. 15486049
-
85.90 €
84.19 € / 5 Gramm
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Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsClotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
Solubility
Soluble in chloroform, DMSO, DMF and alcohols
Notes
Store at room temperature. Incompatible with oxidizing agents.
Chemical Identifiers
| 23593-75-1 | |
| 344.842 | |
| VNFPBHJOKIVQEB-UHFFFAOYSA-N | |
| 2812 | |
| 1-[(2-chlorophenyl)-diphenylmethyl]imidazole |
| C22H17ClN2 | |
| MFCD00057220 | |
| 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole | |
| CHEBI:3764 | |
| C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 |
Specifications
| Clotrimazole | |
| White | |
| C22H17ClN2 | |
| 14,2417 | |
| Soluble in chloroform, DMSO, DMF and alcohols | |
| C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 | |
| 344.842 | |
| CHEBI:3764 |
| 23593-75-1 | |
| 5g | |
| MFCD00057220 | |
| 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole | |
| VNFPBHJOKIVQEB-UHFFFAOYSA-N | |
| 1-[(2-chlorophenyl)-diphenylmethyl]imidazole | |
| 2812 | |
| 344.84 |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Clotrimazole
Signal Word
- Achtung
Hazard Category
- Akute Toxizität Kategorie 4
- LANGFRISTIG GEWÄSSERGEFÄHRDEND Chronisch 1
- AKUT GEWÄSSERGEFÄHRDEND Akut 1
- Schwere Augenschädigung/Augenreizung Kategorie 2
- Hautreizende/-ätzende Wirkung Kategorie 2
Hazard Statement
- H302-Gesundheitsschädlich bei Verschlucken.
- H315-Verursacht Hautreizungen.
- H319-Verursacht schwere Augenreizung.
- H400-Sehr giftig für Wasserorganismen.
- H410-Sehr giftig für Wasserorganismen mit langfristiger Wirkung.
Precautionary Statement
- P280-Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
- P301+P330+P331-BEI VERSCHLUCKEN: Mund ausspülen. KEIN Erbrechen herbeiführen.
- P302+P352-BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/waschen.
- P305+P351+P338-BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
- P312-Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/anrufen.
Supplemental information
- MIXTURE LIST-Enthält: Clotrimazole
Product Title
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