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Invitrogen™ Cripto Monoclonal Antibody (237603)
Rat Monoclonal Antibody
Marke: Invitrogen™ MA561000
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
Spezifikation
| Cripto | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P51865 | |
| TDGF1 | |
| Mouse myeloma cell line NS0-derived recombinant mouse Cripto, Arg26-Gln150. | |
| 150 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2b |
| Flow Cytometry, Inhibition Assays, Immunocytochemistry | |
| 237603 | |
| Unconjugated | |
| TDGF1 | |
| CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR) | |
| Rat | |
| Protein A/G | |
| RUO | |
| 21667 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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