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Gibco™ CTS™ Detachable Dynabeads™ CD8
Beschreibung
Gibco CTS Detachable Dynabeads CD8 are intended for ex vivo isolation of CD8+ T cell subsets. Combined with CTS Detachable Dynabeads Release Buffer (Cat. No. A5588301, A5588302, or A5588303), it is a first-of-its-kind cGMP cell selection technology with an active release mechanism for process development, clinical trial, and commercial manufacturing use. This product is also commonly used with CTS Detachable Dynabeads CD4 (Cat. No. A56994).
Features of CTS Detachable Dynabeads CD8 include:
- Empower users with process flexibility by allowing active release of beads from target cells at any time
- Optimize target cell purity and yield thanks to the active release mechanism that gives users more control
- Provide an automation-friendly solution by working directly with the CTS DynaCellect Magnetic Separation System
- Enable consistent performance in light of biological variability within the starting material
- Suitable for both autologous and allogeneic cell therapy manufacturing processes
These Detachable Dynabeads are meant for direct use with CTS Detachable Dynabeads Release Buffer, which has an active ingredient, biotin, that competitively displaces a biotin derivative on the surface of the beads. This proprietary mechanism allows users to achieve active release of the beads from target cells at any time within their process.
Based on a recommended 4-to-1 bead-to-target-cell ratio (not total nucleated cell number), one 15 mL vial can theoretically isolate up to 1.5 x 109 CD8+ T cells.
CTS Detachable Dynabeads also include a Drug Master File (DMF) to support cross-referencing in regulatory submissions prior to clinical trial and commercial manufacturing use.
Spezifikation
Spezifikation
| Konzentration | 4 x 108 beads/mL |
| Inhalt und Lagerung | CTS™ Detachable Dynabeads™ CD8, 15 mL. Store at 2°C to 8°C with vial upright to keep beads in suspension. |
| Farbe | Brown |
| Material | Polystyrol |
| Produkttyp | Cell Isolation Reagent |
| Zur Verwendung mit (Geräte) | CTS™ DynaCellect™ Magnetic Separation System |
| Produktlinie | CTS Detachable Dynabeads |
| Reinheits- oder Qualitätsgrad | GMP-grade |
| Menge | 15 ml/Fläschchen |
| Versandbedingung | Ships at 2°C to 8°C with wet (not frozen) gel packs. Vial must remain upright to keep beads in suspension. |
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Für die Verwendung in der Forschung oder die Herstellung von zell-, gen- oder gewebebasierten Produkten. ACHTUNG: Nicht für Anwendungen an Menschen oder Tieren geeignet.
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