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Invitrogen™ Cytochrome C Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA579120
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Beschreibung
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human 293T whole cell, human HepG2 whole cell, human HT1080 whole cell, rat kidney tissue, rat skeletal muscle tissue, mouse kidney tissue, mouse skeletal muscle tissue. IHC: Rat Lung Tissue, human skeletal muscle tissue, rat kidney tissue IHC-F: Rat Brain Tissue. ICC/IF: A431 cell, A431 cell, A549 Cell. Flow: CACO-2 cell.
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
Spezifikation
| Cytochrome C | |
| Polyclonal | |
| Unconjugated | |
| Cycs | |
| CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 13063, 25309, 54205 | |
| -20°C | |
| Lyophilized |
| Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 500 μg/mL | |
| PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
| P62897, P62898, P99999 | |
| Cycs | |
| A synthetic peptide corresponding to a sequence at the C-terminus of human Cytochrome C (91-105 aa ERADLIAYLKKATNE). | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat, Rat | |
| Antibody | |
| IgG |
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