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Invitrogen™ DCK Recombinant Rabbit Monoclonal Antibody (5S7P2)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA558194
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Beschreibung
Immunogen sequence: MATPPKRSCP SFSASSEGTR IKKISIEGNI AAGKSTFVNI LKQLCEDWEV VPEPVARWCN VQSTQDEFEE LTMSQKNGGN VLQMMYEKPE RWSFTFQTYA CLSRIRAQLA SLNGKLKDAE KPVLFFERSV YSDRYIFASN LYESECMNET EWTIYQDWHD WMNNQFGQSL ELDGIIYLQA TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE DFKDKYESLV EKVKEFLSTL.
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Spezifikation
| DCK | |
| Recombinant Monoclonal | |
| 1.34 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| P27707, P48769 | |
| DCK | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 5S7P2 | |
| Unconjugated | |
| DCK | |
| DCK; Deoxycytidine kinase; deoxynucleoside kinase | |
| Rabbit | |
| Protein A | |
| RUO | |
| 1633, 79127 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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