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Invitrogen™ Endothelin 1 Monoclonal Antibody (TR.ET.48.5)
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Artikelnummer. 11555722
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Menge:
100 μL
Pakningsstørrelse:
100 Mikroliter
Artikelnummer. Menge unitSize
11555722 100 μL 100 Mikroliter
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Artikelnummer. 11555722

Brand: Invitrogen™ MA3005

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Beskrivelse

Mouse Monoclonal Antibody

MA3-005 detects ET-1 from human, sheep, mouse and rat tissues. This antibody shows little cross-reactivity to related peptides and no known cross-reactivity to non-related peptides. MA3-005 has been successfully used in Western blot, flow cytometry, immunofluorescence, immunohistochemistry, immunocytochemistry, and radioimmune assay procedures. Immunohistochemical staining of ET-1 in human corpus cavernosum tissue with MA3-005 results in staining of endothelial cells. Radioimmune assays using MA3-005 can be used to concentrate ET-1 in solution (e.g. serμm/plasma, milk, urine). This antibody is not recommended for human placenta tissue or HepG2 cells in Western blot applications. For immunohistochemistry with MA3-005 formalin-fixed, paraffin-embedded tissue sections has been used. The MA3-005 antigen is purified human endothelin-1. Studies suggest that this antibody binds to an epitope in the region of ET-1 represented by amino acids 8-16.

The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Endothelin 1
Anwendungen Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon TR.ET.48.5
Konzentration 2.5 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.05% sodium azide
Gen EDN1
Gen-Zugriffsnummer P05305, P22387, P22388, Q9BG76
Gen-Alias ARCND3; Big endothelin 1; Big endothelin-1; Big ET; Big ET 1; Big ET1; BigET; EDN1; endothelin 1; endothelin-1; Et; ET1; ET-1; HDLCQ7; PPET1; ppET-1; preproendothelin; preproendothelin-1; preproET; QME
Gensymbole EDN1
Wirtsspezies Mouse
Immunogen Pure endothelin-1 conjugated to KLH.
Reinigungsverfahren Affinity chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 13614, 1906, 24323, 443498
Zielspezies Human, Mouse, Sheep, Rat
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotype IgG1
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