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Invitrogen™ Epiregulin Monoclonal Antibody (183625)
Mouse Monoclonal Antibody
Marke: Invitrogen™ MA560980
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.
Spezifikation
| Epiregulin | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| O14944 | |
| Ereg | |
| E. coli-derived recombinant human Epiregulin, Val63-Leu108. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| 183625 | |
| Unconjugated | |
| Ereg | |
| Ep; Epiregulin; EPR; ER; EREG; Proepiregulin | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 2069 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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