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PeproTech FGF23 Polyclonal Antibody, PeproTech®, Invitrogen™

Artikelnummer. 17846447
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1 mg
100 μg
50 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
50 Mikrogramm
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17846447 50 μg 50 Mikrogramm
17826597 1 mg 1 Milligramm
17866527 100 μg 100 Mikrogramm
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Artikelnummer. 17846447 Lieferant PeproTech Lieferanten-Nr. 500P31950UG

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Beschreibung

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human FGF-23. Anti-Human FGF-23-specific antibody was purified by affinity chromatography employing an immobilized Human FGF-23 matrix. Sandwich ELISA: To detect Human FGF-23 by sandwich ELISA (using 100 μL/well), a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human FGF-23 (500-P319BT) as a detection antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human FGF-23. Western Blot: To detect Human FGF-23 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human FGF-23 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia, a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen FGF23
Anwendungen ELISA, Western Blot
Klassifikation Polyclonal
Konjugat Unconjugated
Zusammensetzung PBS with no preservative
Gen FGF23
Gen-Zugriffsnummer Q9GZV9
Gen-Alias ADHR; FGF; Fgf23; FGF-23; FGFN; Fibroblast growth factor; Fibroblast growth factor 23; Fibroblast growth factor 23 C-terminal peptide; Fibroblast growth factor 23 N-terminal peptide; HPDR2; HYPF; Phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor; UNQ3027/PRO9828
Gensymbole FGF23
Wirtsspezies Rabbit
Immunogen E.coli-derived, 25.5kDa Recombinant Human FGF-2.
Reinigungsverfahren Affinity chromatography
Menge 50 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 8074
Zielspezies Human
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Lyophilized
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