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Glypican 3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Spezifikation
| Antigen | Glypican 3 |
|---|---|
| Konzentration | 0.37 mg/mL |
| Anwendungen | Western Blot, Immunohistochemistry (Paraffin) |
| Klassifikation | Polyclonal |
| Konjugat | Unconjugated |
Beschreibung
GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predomitly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.Spezifikation
| Glypican 3 | |
| Western Blot, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P51654 | |
| 2719 | |
| Glypican 3 Fusion Protein Ag10129 | |
| Primary | |
| -20°C | |
| GPC3 |
| 0.37 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| DGSX, Glypican 3, GPC3, GTR2 2, Intestinal protein OCI 5, MXR7, OCI 5, OCI5, SDYS, SGB, SGBS, SGBS1 | |
| GPC3 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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