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Invitrogen™ Human ADAMTS4 (aa 104-195) Control Fragment Recombinant Protein

Produktkode 30203023
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Menge:
100 μl
Conditionnement:
100 Mikroliter
Code produit. Menge unitSize
30203023 100 μl 100 Mikroliter
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Code produit. 30203023

Marque: Invitrogen™ RP106333

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
TRUSTED_SUSTAINABILITY

Spécification

Zugriffsnummer O75173
Konzentration ≥5.0 mg/mL
Zur Verwendung mit (Anwendung) Blocking Assay, Control
Zusammensetzung 1 M urea, PBS with no preservative; pH 7.4
Gen-ID (Entrez) 9507
Name Human ADAMTS4 (aa 104-195) Control Fragment
Menge 100 μl
Kennzeichnung RUO
Gen-Alias 3830423K05; a disintegrin and metallopeptidase with thrombospondin motifs 4; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif, 4; ADAMs; ADAM-TS 4; ADAMTS family member; ADAMTS-2; Adamts4; ADAM-TS4; ADAMTS-4; ADMP-1; Aggrecanase; Aggrecanase 1; aggrecanase-1; disintegrin and metalloproteinase with thrombospondin motifs 2; KIAA0688; metalloendopeptidases; metalloproteinase; mKIAA0688; UNQ769/PRO1563
Gebräuchliche Bezeichnung ADAMTS4
Gensymbol ADAMTS4
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung His-ABP-tag
Sequenz VEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCN
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Expressionssystem E. coli
Form Liquid
Reinheits- oder Qualitätsgrad >80% by SDS-PAGE and Coomassie blue staining
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