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Gibco™ Human APRIL Recombinant Protein, PeproTech®

Artikelnummer. 17852333
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Menge:
10 μg
2 μg
2 x 250 μg
2 x 50 μg
4 x 250 μg
5 x 50 μg
50 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
2 Mikrogramm
250 Mikrogramm
50 Mikrogramm
500 Mikrogramm
Artikelnummer. Menge unitSize
17852333 2 x 50 μg 100 Mikrogramm
17852813 10 μg 10 Mikrogramm
17812843 4 x 250 μg 1 Milligramm
17852613 5 x 50 μg 250 Mikrogramm
17852103 2 μg 2 Mikrogramm
17882333 2 x 250 μg 500 Mikrogramm
17892503 50 μg 50 Mikrogramm
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Artikelnummer. 17852333

Marke: Gibco™ 31010C100UG

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Description

Recombinant Protein

310-10C-01M will be provided as 20 x 50 μg (310-10C-50UG). 310-10C-500 will be provided as 10 x 50 μg (310-10C-50UG). 310-10C-250 will be provided as 5 x 50 μg (310-10C-50UG). 310-10C-100 will be provided as 2 x 50 μg (310-10C-50UG) Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues. *Human APRIL (Catalog Number 310-10C) has replaced Human APRIL (Catalog Number 310-10). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer O75888
Zur Verwendung mit (Anwendung) Control, Bioactivity
Zusammensetzung Protein with no preservative
Gen-ID (Entrez) 8741
Molekulargewicht 16.3 kDa
Name Human APRIL
Reinigungsverfahren Purified
Menge 2 x 50 μg
Quelle Insect cells
Lagerungsbedingungen -20°C
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/μg
Gen-Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Gebräuchliche Bezeichnung APRIL
Gensymbol TNFSF13
Biologische Aktivität Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Produkttyp Protein
Konjugat Unconjugated
Rekombinant Recombinant
Sequenz AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL
Inhalt und Lagerung -20°C
Aktivität Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Expressionssystem Insect cells
Form Lyophilized
Reinheits- oder Qualitätsgrad ≥ 95% by SDS-PAGE gel and HPLC analyses.
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