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Gibco™ Human BMP-4 Recombinant Protein

Artikelnummer. 11330852
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Menge:
1 mg
10 μg
100 μg
Packungsgröße:
1 Stück
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Nur für Forschungszwecke. Die Anwendung muss den Produktanweisungen entsprechen.

Artikelnummer. 11330852

Marke: Gibco™ PHC9534

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256.50 EUR gültig bis 2025-12-31
BESTER Aktionspreis! Benutzen Sie den Promotions-Code "24159" um Ihren Promotions-Preis zu erhalten.
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Nur für Forschungszwecke. Die Anwendung muss den Produktanweisungen entsprechen.

Beschreibung

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human BMP-4 in 4 mM HCl containing 0.1% human serum albumin. Further dilutions should be made in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA. Storage: Store this lyophilized preparation at =-20°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at =-20°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
TRUSTED_SUSTAINABILITY

Spezifikation

Zugriffsnummer P12644, P21275
Zur Verwendung mit (Anwendung) Bioactivity
Zusammensetzung HCl with no preservative
Gen-ID (Entrez) 12159, 652
Molekulargewicht 34 kDa
Name Human BMP-4
Reinigungsverfahren Purified
Menge 10 μg
Lagerungsbedingungen -20°C
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/μg
Gen-Alias BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Gebräuchliche Bezeichnung BMP4
Gensymbol BMP4
Biologische Aktivität ED50 = 2 - 10 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Produkttyp Protein
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Inhalt und Lagerung -20°C
Klassifikation Carrier-Free
Aktivität ED50 = 2 - 10 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Bioassay Induction of alkaline phosphatase in ATDC5 cells
Endotoxin-Gehalt <1 EU/ml
Versandbedingung Dry Ice
Expressionssystem HEK293 cells
Proteinfamilie Growth Factors & Receptors
Proteinform Recombinant, Ligand
Form Lyophilized
Protein-Subtyp BMPs (Bone Morphogenetic Proteins) & Related Factors
Forschungskategorie Bone Research, Stem Cell Research, Differentiation
Produktlinie Gibco
Reinheits- oder Qualitätsgrad >95% by SDS-PAGE
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