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Gibco™ Human CD30 Ligand (soluble) Recombinant Protein, PeproTech®
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Menge:
1 mg
10 μg
100 μg
250 μg
50 μg
500 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
250 Mikrogramm
50 Mikrogramm
500 Mikrogramm
Beschreibung
Recombinant Human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His-Tag. The calculated molecular weight of Recombinant Human sCD30L is 21.3 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
Spezifikation
Spezifikation
| Zugriffsnummer | P32971 |
| Zur Verwendung mit (Anwendung) | Functional Assay |
| Zusammensetzung | protein with no preservative |
| Gen-ID (Entrez) | 944 |
| Molekulargewicht | 21.3 kDa |
| Name | Human CD30 Ligand (soluble) |
| Menge | 1 mg |
| Quelle | CHO cells |
| Kennzeichnung | RUO |
| Endotoxin-Konzentration | <1 EU/ μg |
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