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Gibco™ Human HGF Recombinant Protein, PeproTech®
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Menge:
1 mg
100 μg
25 μg
250 μg
5 μg
500 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
25 Mikrogramm
250 Mikrogramm
5 Mikrogramm
500 Mikrogramm
Beschreibung
Recombinant Human HGF, sourced from HEK293 cells, is a 79.4 kDa polypeptide consisting of 695 amino acid residues. As a result of glycosylation, Recombinant Human HGF migrates with an apparent molecular mass of approximately 68-85 kDa by SDS-PAGE gel, under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
Spezifikation
Spezifikation
| Zugriffsnummer | P14210 |
| Zur Verwendung mit (Anwendung) | Functional Assay |
| Zusammensetzung | protein with no preservative |
| Gen-ID (Entrez) | 3082 |
| Molekulargewicht | 79.4 kDa |
| Name | Human HGF |
| Menge | 250 μg |
| Quelle | HEK293 cells |
| Kennzeichnung | RUO |
| Endotoxin-Konzentration | <1 EU/ μg |
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