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Gibco™ Human IL-4 Recombinant Protein, PeproTech®
Beschreibung
Recombinant Human IL-4 is a 15.1 kDa globular protein containing 130 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Spezifikation
Spezifikation
| Zugriffsnummer | P05112 |
| Zur Verwendung mit (Anwendung) | ELISA, Functional Assay, Western Blot |
| Zusammensetzung | protein with no preservative |
| Gen-ID (Entrez) | 3565 |
| Molekulargewicht | 15.1 kDa |
| Name | Human IL-4 |
| Menge | 100 μg |
| Quelle | E. coli |
| Kennzeichnung | RUO |
| Endotoxin-Konzentration | <1 EU/ μg |
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