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Gibco™ Human OX40 Ligand (soluble) Recombinant Protein, PeproTech®
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Menge:
1 mg
10 μg
100 μg
2 μg
250 μg
500 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
2 Mikrogramm
250 Mikrogramm
500 Mikrogramm
Beschreibung
Recombinant OX40L is a glycosylated 133 amino acid protein corresponding to the extracellular TNF homologous domain of the full length transmembrane protein. It migrates with an apparent molecular mass of 15.5-25.0 kDa on SDS-PAGE. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Spezifikation
Spezifikation
| Zugriffsnummer | P23510 |
| Zur Verwendung mit (Anwendung) | Control, ELISA Standard, Binding Assay, Bioactivity |
| Zusammensetzung | Protein with no preservative |
| Gen-ID (Entrez) | 7292 |
| Molekulargewicht | 15.4 kDa |
| Name | Human OX40 Ligand (soluble) |
| Reinigungsverfahren | Purified |
| Menge | 100 μg |
| Quelle | Insect cells |
| Lagerungsbedingungen | -20°C |
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