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Invitrogen™ Human PACS2 (aa 612-732) Control Fragment Recombinant Protein
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Menge:
100 μl
Packungsgröße:
100 Mikroliter
Beschreibung
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51575 (PA5-51575. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Spezifikation
Spezifikation
| Zugriffsnummer | Q86VP3 |
| Konzentration | ≥5.0 mg/mL |
| Zur Verwendung mit (Anwendung) | Blocking Assay, Control |
| Zusammensetzung | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-ID (Entrez) | 23241 |
| Name | Human PACS2 (aa 612-732) Control Fragment |
| Menge | 100 μl |
| Kennzeichnung | RUO |
| Gen-Alias | 6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; Kiaa0602; mKIAA0602; Pacs1l; PACS1-like protein; Pacs2; PACS-2; Phosphofurin acidic cluster sorting protein 2 |
| Gebräuchliche Bezeichnung | PACS2 |
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