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Invitrogen™ Human SHB (aa 340-400) Control Fragment Recombinant Protein
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Menge:
100 μl
Packungsgröße:
100 Mikroliter
Beschreibung
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65701 (PA5-65701. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain-containing proteins to tyrosinephosphorylated sites, an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function. Shb (SH2 domain-containing adapter protein b), Shd (SH2 domain-containing adapter protein d), She (SH2 domain-containing adapter protein e) and Shf(SH2 domain-containing adapter protein f) are SH2 domain-containing proteins that play various roles throughout the cell.
Spezifikation
Spezifikation
| Zugriffsnummer | Q15464 |
| Konzentration | ≥5.0 mg/mL |
| Zur Verwendung mit (Anwendung) | Blocking Assay, Control |
| Zusammensetzung | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-ID (Entrez) | 6461 |
| Name | Human SHB (aa 340-400) Control Fragment |
| Menge | 100 μl |
| Kennzeichnung | RUO |
| Gen-Alias | bA3J10.2; BC028832; SH2 domain containing adaptor protein B; SH2 domain-containing adapter protein B; Shb; SHB (Src homology 2 domain containing) adaptor protein B; SHB adaptor protein (a Src homology 2 protein); Src homology 2 domain containing adaptor protein B; src homology 2 domain-containing transforming protein B |
| Gebräuchliche Bezeichnung | SHB |
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