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Gibco™ Human TACI Recombinant Protein, PeproTech®

Artikelnummer. p-7246124
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Menge:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
500 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
20 Mikrogramm
250 Mikrogramm
5 Mikrogramm
500 Mikrogramm
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Artikelnummer. 17842073

Marke: Gibco™ 31017100UG

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Description

Recombinant Protein

310-17-1MG will be provided as 2 x 500 μg (310-17-500UG). Recombinant Human TACI is a soluble 159 amino acid polypeptide (17.8 kDa) comprising the TNFR homologous, cysteine-rich extracellular domain of the TACI protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer O14836
Zur Verwendung mit (Anwendung) ELISA, Functional Assay, Western Blot
Zusammensetzung protein with no preservative
Gen-ID (Entrez) 23495
Molekulargewicht 17.8 kDa
Name Human TACI
Menge 100 μg
Quelle E. coli
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/ μg
Gen-Alias 1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13 B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13 B; tumor necrosis factor receptor superfamily member 13 B; tumor necrosis factor receptor superfamily, member 13 B
Gebräuchliche Bezeichnung TACI
Gensymbol TNFRSF13B
Biologische Aktivität Determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml
Konjugat Unconjugated
Rekombinant Recombinant
Sequenz SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV
Inhalt und Lagerung -20°C
Expressionssystem E. coli
Form Lyophilized
Reinheits- oder Qualitätsgrad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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