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Gibco™ Human Thrombomodulin (BDCA-3) Recombinant Protein, PeproTech®

Artikelnummer. 17881643
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Menge:
1 mg
10 μg
100 μg
2 μg
250 μg
500 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
2 Mikrogramm
250 Mikrogramm
500 Mikrogramm
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Artikelnummer. 17881643

Marke: Gibco™ 10058100UG

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Beschreibung

Recombinant Protein

Recombinant Human Thrombomodulin is a 51.4 kDa, 491-amino-acid length glycoprotein containing the extracellular domain of thrombomodulin. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
TRUSTED_SUSTAINABILITY

Spezifikation

Zugriffsnummer P07204
Zur Verwendung mit (Anwendung) Functional Assay
Zusammensetzung protein with no preservative
Gen-ID (Entrez) 7056
Molekulargewicht 51.4 kDa
Name Human Thrombomodulin (BDCA-3)
Menge 100 μg
Quelle HEK293 cells
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/ μg
Gen-Alias AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM
Gebräuchliche Bezeichnung Thrombomodulin (CD141)
Gensymbol THBD
Biologische Aktivität Measured by its ability to activate protein C induced cleavage of the chromogenic substrate, BOC-Asp-Pro Arg-AMC in the presence of thrombin. The specific activity is greater than 500 pmoles/min/ug.
Konjugat Unconjugated
Rekombinant Recombinant
Sequenz APAEPQPGGS QCVEHDCFAL YPGPATFLNA SQICDGLRGH LMTVRSSVAA DVISLLLNGD GGVGRRRLWI GLQLPPGCGD PKRLGPLRGF QWVTGDNNTS YSRWARLDLN GAPLCGPLCV AVSAAEATVP SEPIWEEQQC EVKADGFLCE FHFPATCRPL AVEPGAAAAA VSITYGTPFA ARGADFQALP VGSSAAVAPL GLQLMCTAPP GAVQGHWARE APGAWDCSVE NGGCEHACNA IPGAPRCQCP AGAALQADGR SCTASATQSC NDLCEHFCVP NPDQPGSYSC MCETGYRLAA DQHRCEDVDD CILEPSPCPQ RCVNTQGGFE CHCYPNYDLV DGECVEPVDP CFRANCEYQC QPLNQTSYLC VCAEGFAPIP HEPHRCQMFC NQTACPADCD PNTQASCECP EGYILDDGFI CTDIDECENG GFCSGVCHNL PGTFECICGP DSALARHIGT DCDSGKVDGG DSGSGEPPPS PTPGSTLTPP A
Inhalt und Lagerung -20°C
Expressionssystem HEK293 cells
Form Lyophilized
Reinheits- oder Qualitätsgrad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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