missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Human TNPO2 (aa 331-363) Control Fragment Recombinant Protein
Click to view available options
Menge:
100 μl
Packungsgröße:
100 Mikroliter
Beschreibung
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67176 (PA5-67176. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Spezifikation
Spezifikation
| Zugriffsnummer | O14787 |
| Konzentration | ≥5.0 mg/mL |
| Zur Verwendung mit (Anwendung) | Blocking Assay, Control |
| Zusammensetzung | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-ID (Entrez) | 30000 |
| Name | Human TNPO2 (aa 331-363) Control Fragment |
| Menge | 100 μl |
| Kennzeichnung | RUO |
| Gen-Alias | 1110034O24Rik; AA414969; AI464345; AI852433; importin 3; IPO3; karyopherin (importin) beta 2 b; karyopherin beta 2 b, transportin; karyopherin beta-2 b; Knpb2b; Kpnb2b; TNPO2; transportin 2; transportin 2 (importin 3, karyopherin beta 2 b); transportin-2; TRN2 |
| Gebräuchliche Bezeichnung | TNPO2 |
| Mehr anzeigen |
Berichtigung von Produktinhalten
Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.
Name des Produkts
Haben Sie Verbesserungsvorschläge?Übermitteln Sie eine inhaltliche Korrektur