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Invitrogen™ IGF1R (CD221) Biosimilar Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
477.00 € - 1204.00 €
Spezifikation
| Antigen | IGF1R (CD221) Humanized Biosimilar |
|---|---|
| Konzentration | 1 mg/mL |
| Inhalt und Lagerung | -20°C, Avoid Freeze/Thaw Cycles |
| Anwendungen | ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance |
| Klassifikation | Recombinant Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
30283224
|
Invitrogen™
MA559427 |
100 μg |
477.00 €
100 Mikrogramm |
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|
30282893
|
Invitrogen™
MA559428 |
1 mg |
1204.00 €
1 Milligramm |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Immunomedics patent anti-IGF-1R.
IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers. The protein is a tetramer consisting of two alpha, and two beta subunits. The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2. Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136. The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.Spezifikation
| IGF1R (CD221) Humanized Biosimilar | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Recombinant Monoclonal | |
| Lyophilized | |
| IgG1 | |
| Human | |
| Primary | |
| Protein A |
| 1 mg/mL | |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| Unconjugated | |
| Human | |
| RUO | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Antibody |
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