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Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), PE-eFluor™ 610, eBioscience™, Invitrogen™

Beschreibung
The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine.
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Spezifikation
Spezifikation
| Antigen | IL-2 |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Klon | JES6-5H4 |
| Konzentration | 0.2 mg/mL |
| Konjugat | PE-eFluor 610 |
| Zusammensetzung | PBS with 0.09% sodium azide; pH 7.2 |
| Gen | IL2 |
| Gen-Zugriffsnummer | P04351 |
| Gen-Alias | aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF |
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