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Invitrogen™ IL-5 Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
Marke: Invitrogen™ MA551008
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Beschreibung
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Spezifikation
| IL-5 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
| P04401, P05113, Q08125 | |
| Il5 | |
| Recombinant Human IL5 protein, Ile20-Ser134 (Accession #P05113). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 κ |
| Western Blot, Immunohistochemistry (Paraffin), Western Blot | |
| C1 | |
| Unconjugated | |
| Il5 | |
| B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 16191, 24497, 3567 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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