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Invitrogen™ Influenza A M2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA532233
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Beschreibung
Recommended positive controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates, H1N1-infected H1299. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2). M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA. M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain. The M2 protein has been found to play a role in Influenza replication and assembly of virion particles. Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication.
Spezifikation
| Influenza A M2 | |
| Polyclonal | |
| Unconjugated | |
| Influenza M2 | |
| Recombinant protein corresponding to Influenza A virus M2 (matrix protein) (A/Puerto Rico/8/1934(H1N1). The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunomicroscopy, Western Blot, Immunocytochemistry | |
| 0.61 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| Virus | |
| Antibody | |
| IgG |
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